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Growth Hormone Deficiency

What is Growth Hormone Deficiency?

Growth Hormone Deficiency is a rare condition caused by the pituitary gland not producing enough somatotropin. Somatotropin is a hormone that’s job is to stimulate growth and cell reproduction within the body. The hormone is necessary for normal growth and development, both of which are necessary for healthy muscles, tissues and bones.   

What are the symptoms of Growth Hormone Deficiency?

Growth Hormone Deficiency primarily impacts children. However, the symptoms from childhood can continue into adulthood. 

Childhood symptoms include:

  • Short Stature
  • Low growth velocity for age and pubertal stage- below the 3rd percentile
  • Increased amount of fat around the waist
  • Younger appearance than other children around the same age

Adult symptoms may include:

  • Continued GHD from childhood
  • Anxiety or depression
  • Decreased muscle mass

What causes Growth Hormone Deficiency?

There are three types of Growth Hormone Deficiency, Congenital, Acquired, and Idiopathic:

  • Congenital Growth Hormone Deficiency is a condition that children are born with, however is rarely a genetic disorder. Rather, the condisition stems from damage to the pituitary gland or hypothalamus. 
  • Acquired Growth Hormone Deficiency is developed after birth. Various health-related issues may cause growth hormone deficiency, including: 
    • Hormonal problems related to the hypothalamus or pituitary glands
    • Poor blood supply to the pituitary gland
    • Severe head injury, brain tumor, infection or surgery
    • Radiation treatments to the brain
  • Idiopathic Growth Hormone Deficiency has no diagnosable cause. 

Children with GHD can often appear smaller, or less mature than other children the same age.

Approximately 1 in 7,000 children are diagnosed with GHD at birth.

How is Growth Hormone Deficiency treated?

Growth Hormone Deficiency is treated with growth hormone replacement therapy. Somatropin, a man-made growth hormone, has been approved by the Food and Drug Administration for use in treating Growth Hormone Deficiency. Somatropin, is similar to somatotropin, the hormone produced naturally by the body.  Growth hormone replacement therapy is an injection administered by the patient or their caregiver. 

How does Noble help me manage my Growth Hormone Deficiency?

At Noble Health Services, we offer a variety of medications to help you treat your symptoms. We help you manage your condition through our Signature Care Program, which includes medication delivery, 24/7/365 on-call support, benefits and co-pay assistance and more. For more information on what Growth Hormone Deficiency medications we offer, please view the Growth Hormone Deficiency enrollment form.

For more information about Growth Hormone Deficiency, contact the following resources:

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